NFL Week 5 Injury Report: Key Players Missing Ahead of Weekend Games

As we head into Week 5 of the 2025 NFL season, injuries are dominating the conversation around the league. After a tough Week 4, several players found themselves on injured reserve, leaving teams scrambling to adjust before this weekend’s games. Here’s a rundown of the latest injury news from various teams competing this week.

In Minnesota, the offensive line is set to miss three starters. This could create a challenging situation when facing off against Cleveland’s powerful defense, potentially putting their quarterback under significant pressure. They will also be without Van Ginkel, a notable defensive player. Meanwhile, Conklin participated fully in practice Friday, providing some hope for the offense.

The Jets look to be in better shape compared to the Cowboys, who might enter their game without up to four starting offensive linemen. This situation is compounded by the fact that their top wide receiver and a handful of defensive players could also be sidelined. The Jets will need to capitalize on this opportunity.

In Baltimore, things are particularly dire. With Lamar Jackson out, the team will rely on Cooper Rush to step in. However, the secondary has taken hits, leaving them vulnerable against a tough matchup with Houston.

The Broncos are coming in relatively healthy, with minor bumps and bruises among players. Meanwhile, the Colts will need to navigate their game against the Raiders without key players, potentially impacting their offensive strategy.

In New Orleans, the situation is complicated too. The offensive line may be missing vital components, and the pass rush could suffer due to injuries to several players. The Dolphins, shorthanded at wide receiver, will need to find a way to forge ahead against their opponents.

Despite the ups and downs, teams are working diligently to prepare for their matchups, hoping injuries don’t derail their seasons. As always, keep an eye on updates as we head to game day, as last-minute changes can happen.